First Published Papers on IMRIS Suites Report Positive Results

September 27, 2011
Author: IMRIS Inc.

Winnipeg, Manitoba, September 26, 2011 -- IMRIS Inc. (NASDAQ: IMRS; TSX: IM) ("IMRIS" or
the “Company”) announced that the first published results on the early clinical experiences at
hospitals using the IMRIS system, highlight a number of positive findings for procedures and
patient outcomes resulting from utilization of the intraoperative MRI capabilities available in IMRIS

The studies which were conducted at hospitals in three different countries each concluded that the
IMRIS system can be safely integrated into neurosurgical workflows and enable intraoperative
modification of surgical strategy in a range of neurosurgical procedures.

The studies included 180 patients treated from April 2008 to July 2009 at the Washington
University School of Medicine in St. Louis, Missouri, USA (Chicoine MR., et al); 45 patients treated
between July 2008 and July 2009 at PLA 301 Hospital in Beijing, China, (Xiaolei Chen, et al); and
120 patients who underwent procedures between January 2009 and November 2009 at University
of Calgary Foothills Hospital in Calgary, Alberta, Canada, (Michael J. Lang, et al).
Highlights include:

• In 41% of all cases in the Washington University School of Medicine study and in 48.9% of all
cases included in the study at PLA 301 Hospital, the surgeon modified the surgical procedure
based upon the intraoperative MR imaging information provided by the IMRIS suite.

• Gross/near total tumor resection was achieved in 93% of patients with gliomas in the
Washington University School of Medicine study, compared with 65% for procedures that did
not utilize the intraoperative MR imaging capabilities in the same timeframe.

• Gross/near total tumor resection was achieved in 76.9% of the pituitary adenoma procedures in
the PLA 301 Hospital preliminary clinical experience which compared with 38.5% of the
procedures having achieved gross/near total tumor resection prior to the intraoperative MR

• From clinical experience with 120 patients, the University of Calgary Foothills Hospital study
found that intraoperative imaging resulted in modification to surgery in a substantial number of
patients and concluded that intraoperative imaging at 3.0T is safe, reliable and capable of
directing image guided surgery with exceptional image quality.

Links to Abstracts for the studies referenced in this news release are available at the U.S. National
Library of Medicine National Institutes of Health database website:

Globally, more than 6,000 procedures have now been completed in IMRIS suites which are
designed to provide timely imaging information to assist clinicians in making better decisions for
improved patient outcomes. IMRIS suites allow a high field MR scanner to move into an operating
room on demand before, during and after procedures without moving the patient.

The patient is not required to be transported for scanning, so the optimum patient positioning is
always maintained. Clinical workflow and access to the patient is not impacted and the MR
scanner is removed completely from the operating room when imaging is complete. This ensures
a high degree of safety for both the patient and the surgical environment. As well, when not in use
for intraoperative imaging, the MR scanner is available for diagnostic imaging. To date, more than
100 imaging enabled rooms have been selected by leading medical institutions around the world.

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